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Acute and Subchronic Oral Toxicity Evaluation of Herbal Formulation: Piper crocatum Ruiz and Pav., Typhonium flagelliforme (Lodd.) Blume, and Phyllanthus niruri L. in Sprague-Dawley Rats.

Retno MurwantiA NurrochmadAndayana P GaniEdiati SasmitoAngela E EdwinaMayang K ChandraF H SuryawanA R Wardananull NataliaJelita L S R Budiningsih
Published in: Journal of toxicology (2023)
Analyses of these results suggest that the long-term oral administration of the SKM product for 90 days does not cause subchronic toxicity.
Keyphrases
  • oxidative stress
  • liver failure
  • drug delivery
  • respiratory failure
  • aortic dissection
  • oxide nanoparticles
  • hepatitis b virus