Prevalence of major adverse cardiovascular events among Saudi patients with systemic lupus erythematosus compared with the general population: updates from the national SLE and PURE cohorts.
Ibrahim AlmaghlouthKawther Ghassan BohuligaBoshra AlanaziBushra Khaled AlhawsaAbdulaziz Mohammed AlabdulkareemWael AlqarawiKazi Nur AsfinaNajma KhalilHebatallah Hamed AliMohammed BedaiwiAos A AboabatJiandong SuTariq Asef AlamFehaid Ghali AlanaziMohammed A OmairAbdurhman S AlarfajHaya M AlmalaqMostafa Al ShamiriKhalid F AlhabibPublished in: Lupus science & medicine (2024)
Patients with SLE have a significantly higher risk of developing MACE than the general population. This risk is not well explained by traditional risk factors, which may explain the failure of CVD risk scores to stratify patients with SLE adequately. Further studies are needed to understand CVD risk's pathogenesis in SLE and mitigate it.