Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities.
Nicolas A CrossleyAndre ZugmanFrancisco Reyes-MadrigalLeticia Sanguinetti CzepielewskiMariana N CastroAna M Diaz-ZuluagaJulian A Pineda-ZapataRamiro ReckziegelAry GadelhaAndrea JackowskiCristiano NotoLuz M AlliendeBarbara IruretagoyenaTomas OssandonJuan P Ramirez-MahalufCarmen P CastañedaAlfonso Gonzalez-ValderramaRuben NacharPablo León-OrtizJuan UndurragaCarlos López-JaramilloSalvador M GuinjoanClarissa S GamaCamilo de la Fuente-SandovalRodrigo A Bressannull nullPublished in: The British journal of psychiatry : the journal of mental science (2021)
Our results highlight the interplay between environment, particularly poverty, and individual characteristics in psychosis. This is particularly important for harsh environments such as low- and middle-income countries, where potentially less brain vulnerability (less grey matter loss) is sufficient to become unwell in adverse (poor) environments.