Tailoring the SWIR emission of gold nanoclusters by surface ligand rigidification and their application in 3D bioimaging.

Xavier Le Guével Karl David Wegner Christian Würth Vladimir A BaulinB MusnierV JosserandUte Resch-Genger Jean-Luc Coll

Published in: Chemical communications (Cambridge, England) (2022)

The influence of solvent polarity and surface ligand rigidification on the SWIR emission profile of gold nanoclusters with an anistropic surface was investigated. A strong enhancement of the SWIR emission band at 1200 nm was observed when measuring in different local environments: in solution, in polymer composites, and in solids. SWIR in vivo imaging of mice assisted by deep learning after intravenous administration of these gold nanoclusters provides high definition pseudo-3D views of vascular blood vessels.

Keyphrases

fluorescent probe
sensitive detection
deep learning
solid state
living cells
silver nanoparticles
label free
high resolution
quantum dots
energy transfer
high dose
machine learning
type diabetes
low dose
skeletal muscle
high fat diet induced
fluorescence imaging
wild type