In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome.
Maksim KhotimchenkoNicholas E BrunkMark S HixonDaniel M WaldenHypatia HouKaushik ChakravartyJyotika VarshneyPublished in: Pharmaceutical research (2022)
Our analysis suggests this novel combinatorial therapeutic approach inducing DPP4 and Il-17a suppression has a high likelihood of ameliorating a significant portion of the clustered clinical risk in metabolic syndrome.