Low-grade astrocytoma in the setting of a developmental venous anomaly.
Meghan ConnorsWilliam PadenPhillip B StormAngela J WaandersShih-Shan LangPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2019)
Developmental venous anomalies (DVAs) are the most common type of cerebrovascular malformation and are considered benign. There are a few literature studies associating DVA with brain tumors, suggesting a possible underlying predisposition in these patients for tumor neogenesis. We report a 7-year-old female with a complex DVA who developed a low-grade astrocytoma in the opposite hemisphere. With analysis of a comprehensive solid tumor panel and imaging, we describe the possible association of an underlying susceptibility to neoplastic growth in the presence of a vascular malformation.