A percutaneous approach to create tricuspid regurgitation in swine: a model for transcatheter tricuspid valve therapy assessment.

Qian YanZhi Wei ChanJeremy Xian Wei GohJimmy Kim Fatt HonJulian Chi Leung WongWilliam Kok-Fai KongEdgar Lik Wui Tay

Published in: Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs (2021)

Severe tricuspid regurgitation can be created by a simple and effective percutaneous approach with a grasping forceps in swine model and right heart dilation can be observed consistently at one-month follow-up. This model will be valuable in pre-clinical studies for developing new tricuspid valve repair or replacement technique to treat severe tricuspid regurgitation.

Keyphrases

aortic valve
aortic stenosis
transcatheter aortic valve replacement
mitral valve
ejection fraction
left ventricular
minimally invasive
heart failure
coronary artery disease
early onset
ultrasound guided
radiofrequency ablation
mesenchymal stem cells
clinical evaluation