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Direct Synthesis of Sulfinylated Benzofulvenes via BF3·Et2O-Promoted Cascade Reactions of Arylsulfinic Acids with 1,3-Enynes.

Zhen ZhangAnni LiBeibei ZhaoPinhua LiLei WangTao Miao
Published in: Organic letters (2021)
A novel and efficient method for the selective synthesis of sulfinylated benzofulvenes has been developed through the BF3·Et2O-promoted electrophilic addition/cyclization of 1,3-enynes. This metal-free cascade reaction employs readily accessible arylsulfinic acids as sulfinyl cation sources at room temperature and provides a wide range of functionalized benzofulvenes in good to excellent yields under mild conditions.
Keyphrases
  • room temperature
  • ionic liquid
  • quantum dots
  • mass spectrometry
  • molecularly imprinted
  • simultaneous determination
  • liquid chromatography