Blocking antibodies induced by allergen-specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model.

Caterina VizzardelliM GindlS Roos Christian MöbsB NaglF ZimmannV SexlL KennerA NeunkirchnerG J ZlabingerW F PicklW PfütznerBarbara Bohle

Published in: Allergy (2017)

Our data demonstrate that post-AIT sera with IgE-blocking activity ameliorate allergic airway inflammation in a human/mouse chimeric model of respiratory allergy independently of AIT-induced cellular changes.

Keyphrases

endothelial cells
cell therapy
high glucose
induced pluripotent stem cells
allergic rhinitis
atopic dermatitis
stem cells
diabetic rats
big data
machine learning
oxidative stress
artificial intelligence
respiratory tract
deep learning
stress induced
data analysis