Clinical efficacy and safety in patients treated with teicoplanin with a target trough concentration of 20 μg/mL using a regimen of 12 mg/kg for five doses within the initial 3 days.
Takashi UedaYoshio TakesueKazuhiko NakajimaKaoru IchikiKaori IshikawaYoshiko TakaiKumiko YamadaToshie TsuchidaNaruhito OtaniYoshiko TakahashiMika IshiharaShingo TakuboHiroki IkeuchiMotoi UchinoTakeshi KimuraPublished in: BMC pharmacology & toxicology (2020)
A target Cmin ≥ 20 μg/mL might improve early clinical responses during the treatment of difficult MRSA infections using 12 mg/kg teicoplanin for five doses within the initial 3 days.
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