Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.

Yuhang Xi Yunlong GeDaoyuan HuTian XiaJialiang ChenChi ZhangYubin CuiHengjun Xiao

Published in: The journal of sexual medicine (2023)

Administration of CSD peptide significantly retarded collagen synthesis in CCSMCs, limited CC fibrosis, and prevented ED via confrontation of TGF-β1/Smad signaling in BCNI rats.

Keyphrases

transforming growth factor
emergency department
epithelial mesenchymal transition
high glucose
diabetic rats
case report
liver fibrosis
mouse model
oxidative stress
signaling pathway
wound healing
tissue engineering