Streptococcus mitis enhances metal-induced apoptosis in reconstructed human gingiva but not skin.
Yan ZhangLin ShangSanne RoffelSander W SpiekstraDongmei DengSusan Gibbs
Published in: Toxicology in vitro : an international journal published in association with BIBRA (2024)
Our study supports the finding that metals have irritant, cytotoxic properties resulting in apoptosis when leaching into skin or gingiva. Particularly for gingiva, commensal microbes exaggerate this detrimental effect.