IL-3-producing basophils are required to exacerbate airway hyperresponsiveness in a murine inflammatory model.
R Rignault-BricardF MachavoineS MecheriO HermineE SchneiderM DyMaria C Leite-de-MoraesPublished in: Allergy (2018)
IL-3-dependent basophils promote Th2 allergic AHR, which designates the IL-3/basophil axis as a promising therapeutic target for the treatment of basophil-dependent asthma.