The effects of direct hemoperfusion using a polymyxin B-immobilized column in a pig model of severe Pseudomonas aeruginosa pneumonia.

Gianluigi Li BassiJoan Daniel MartiEli Aguilera XiolTalitha ComaruFrancesca De RosaMontserrat RigolSilvia TerraneoMariano RinaudoLaia FernandezMiguel FerrerAntoni Torres

Published in: Annals of intensive care (2016)

In mechanically ventilated pigs with severe P. aeruginosa pneumonia, PMX-HP does not have any valuable clinical benefit, and studies are warranted to fully evaluate a potential role of PMX-HP in septic shock associated with severe pulmonary infections.

Keyphrases

septic shock
pseudomonas aeruginosa
early onset
cystic fibrosis
pulmonary hypertension
acute respiratory distress syndrome
drug induced
ionic liquid
gram negative
multidrug resistant
respiratory failure
climate change
high resolution
solid phase extraction