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The Phytophthora parasitica effector AVH195 interacts with ATG8, attenuates host autophagy, and promotes biotrophic infection.

Serena TestiMarie-Line KuhnValérie AllasiaPascaline AuroyFantao KongGilles PeltierSophie PagnottaJulie CazarethHarald KellerFranck Panabières
Published in: BMC biology (2024)
Taken together, our observations suggest that AVH195 targets ATG8 to attenuate autophagy and prevent associated host cell death, thereby favoring biotrophy during the early stages of the infection process.
Keyphrases
  • cell death
  • endoplasmic reticulum stress
  • cell cycle arrest
  • signaling pathway
  • oxidative stress
  • regulatory t cells
  • dendritic cells
  • immune response
  • cell proliferation