Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes.
Amy MooreMitchell J MachielaMoara MachadoSophia S WangEleanor KaneSusan L SlagerWeiyin ZhouMary CarringtonQing LanRoger L MilneBrenda M BirmannHans-Olov AdamiDemetrius AlbanesAlan A ArslanNikolaus BeckerYolanda BenaventeSimonetta BisanziPaolo BoffettaPaige M BracciPaul BrennanAngela R Brooks-WilsonFederico CanzianNeil CaporasoJacqueline ClavelPierluigi CoccoLucia CondeDavid G CoxWendy CozenKaren CurtinImmaculata De VivoSilvia de SanjoseLenka ForetovaSusan M GapsturHervè GhesquièresGraham G GilesMartha GlennBengt GlimeliusChi GaoThomas M HabermannHenrik HjalgrimRebecca D JacksonMark LiebowBrian K LinkMarc MaynadieJames McKayMads MelbyeLucia MiligiThierry J MolinaAlain MonnereauAlexandra NietersKari E NorthKenneth OffitAlpa V PatelSara PiroVignesh RavichandranElio RiboliGilles SallesRichard K SeversonChristine F SkibolaKarin E SmedbyMelissa C SoutheyJohn J SpinelliAnthony StainesCarolyn StewartLauren R TerasLesley F TinkerRuth C TravisClaire M VajdicRoel C H VermeulenJoseph VijaiElisabete WeiderpassStephanie WeinsteinNicole Wong DooYawei ZhangTongzhang ZhengStephen J ChanockNathaniel RothmanJames R CerhanMichael DeanNicola J CampMeredith YeagerSonja I BerndtPublished in: Journal of translational genetics and genomics (2021)
Our findings support the role of recessive genetic variation in the etiology of CLL and FL; additional research is needed to identify the specific loci associated with NHL risk.