Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina.

Elisa J CamposJoão MartinsDan BrudzewskySandra CorreiaAna R SantiagoDavid Pd WoldbyeAntónio Francisco Ambrósio

Published in: Clinical & experimental ophthalmology (2018)

DM modestly affects the NPY system in the retina and these effects are not prevented by sitagliptin treatment. These observations suggest that DPP-IV enzyme is not underlying the NPY changes detected in the retina induced by type 1 DM.

Keyphrases

diabetic retinopathy
optic nerve
type diabetes
cardiovascular disease
metabolic syndrome
skeletal muscle
weight loss
optical coherence tomography
replacement therapy
smoking cessation