SATB2 protein expression by immunohistochemistry is a sensitive and specific marker of appendiceal and rectosigmoid well differentiated neuroendocrine tumours.
Deepthi HoskoppalJonathan I EpsteinAllen M GownShanna A Arnold EgloffJennifer B GordetskyChanjuan J ShiGiovanna A GiannicoPublished in: Histopathology (2020)
In summary, SATB2 is a sensitive and specific marker for rectal/rectosigmoid and appendiceal WDNETs, and may represent a useful diagnostic tool when these sites of origin are considered in the differential diagnosis.
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