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Health literacy, but not memory, is associated with hippocampal connectivity in adults with low levels of formal education.

Elisa de Paula França ResendeVivian P LaraAna Luisa C SantiagoClarisse V FriedlaenderHoward J RosenJesse A BrownYann CobigoLênio L G SilvaLeonardo Cruz de SouzaLuciana RinconLea T GrinbergFrancisca I P MacielPaulo Caramelli
Published in: Alzheimer's & dementia (Amsterdam, Netherlands) (2024)
A significant link was found between health literacy and hippocampal connectivity.Enhanced hippocampus- ventromedial prefrontal cortex connectivity suggests potential cognitive reserve improvement.Higher cognitive reserve may protect against hippocampal atrophy and neurodegeneration.Health literacy improvements could help prevent cognitive impairment in illiterate populations.Study highlights importance of considering structural racism in brain connectivity research.
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