Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients.
Jaclyn R DanielsJennie Z MaZhijun CaoRichard D BegerJinchun SunLaura SchnackenbergLisa PenceDevasmita ChoudhurySusan T CrowleyDidier PortillaLi-Rong YuPublished in: Kidney360 (2022)
These results suggest concerted changes between survival-related proteins and immune-regulatory chemokines in regulating angiogenesis, endothelial and epithelial remodeling, and kidney cell regeneration, illustrating potential mechanisms of kidney recovery. Thus, this study identifies potential novel predictive biomarkers of kidney recovery in patients with AKI-D.
Keyphrases
- end stage renal disease
- chronic kidney disease
- acute kidney injury
- endothelial cells
- stem cells
- newly diagnosed
- ejection fraction
- small molecule
- single cell
- high throughput
- genome wide
- human health
- prognostic factors
- risk assessment
- mesenchymal stem cells
- patient reported outcomes
- bone marrow
- climate change
- free survival