Benzoazacrown compound: a highly effective chelator for therapeutic bismuth radioisotopes.
Ekaterina V MatazovaBayirta V EgorovaEkaterina A KonopkinaGleb Yu AleshinAnastasia D ZubenkoArtem A MitrofanovKirill V KarpovOlga A FedorovaYurii V FedorovStepan N KalmykovPublished in: MedChemComm (2019)
A new benzoazacrown ligand H4BATA was synthesized and its complexation ability towards bismuth cations was evaluated. Binding of cation occurs at room temperature in a few minutes and formed complex exhibits the same level of inertness as highly stable complex with the well-known H4DOTA in biologically relevant and challenging media under in vivo conditions.