IL-17 signaling in primary sclerosing cholangitis patient-derived organoids.
Ana S Garcia MorenoMaria Eugenia GuicciardiAlexander Q WixomErik JessenJingchun YangSumera Irie IlyasJackie K BianchiFilippo Pinto E VairoKonstantinos N LazaridisGregory J GoresPublished in: Hepatology communications (2024)
PSC and non-PSC patient-derived ECO respond differently to IL-17 stimulation, implicating this pathway in the pathogenesis of PSC.
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