An updated patent review on monoamine oxidase (MAO) inhibitors.
Paolo GuglielmiSimone CarradoriIlaria D'AgostinoCristina CampestreJacobus P PetzerPublished in: Expert opinion on therapeutic patents (2022)
MAO inhibitors here reported exhibit different potencies and isoform selectivity. These compounds are clinically licensed for multi-faceted neurodegenerative pathologies due to their ability to also act against other relevant targets (cholinesterases, inflammation, and oxidative stress). Moreover, the drug repurposing approach is an attractive strategy by which MAO inhibitors may be applied for the treatment of prostate cancer, inflammation, vertigo, and type 1 diabetes.