Thyroid nodules over 4 cm do not have higher malignancy or benign cytology false-negative rates.
Muhammed KizilgulRupendra T ShresthaAngela RadulescuMaria R EvasovichLynn A BurmeisterPublished in: Endocrine (2019)
This study shows that thyroid nodules ≥4 cm do not have a higher malignancy rate at surgery nor higher benign cytology false-negative rate than smaller nodules. Thyroid nodules over 4 cm do not require resection, to rule out malignancy, based on size alone.