Fast automated detection of COVID-19 from medical images using convolutional neural networks.
Shuang LiangHuixiang LiuYu GuXiuhua GuoHongjun LiLi LiZhi-Yuan WuMengyang LiuLixin TaoPublished in: Communications biology (2021)
Coronavirus disease 2019 (COVID-19) is a global pandemic posing significant health risks. The diagnostic test sensitivity of COVID-19 is limited due to irregularities in specimen handling. We propose a deep learning framework that identifies COVID-19 from medical images as an auxiliary testing method to improve diagnostic sensitivity. We use pseudo-coloring methods and a platform for annotating X-ray and computed tomography images to train the convolutional neural network, which achieves a performance similar to that of experts and provides high scores for multiple statistical indices (F1 scores > 96.72% (0.9307, 0.9890) and specificity >99.33% (0.9792, 1.0000)). Heatmaps are used to visualize the salient features extracted by the neural network. The neural network-based regression provides strong correlations between the lesion areas in the images and five clinical indicators, resulting in high accuracy of the classification framework. The proposed method represents a potential computer-aided diagnosis method for COVID-19 in clinical practice.
Keyphrases
- coronavirus disease
- convolutional neural network
- deep learning
- neural network
- sars cov
- artificial intelligence
- computed tomography
- machine learning
- respiratory syndrome coronavirus
- healthcare
- clinical practice
- magnetic resonance
- gene expression
- single cell
- genome wide
- dual energy
- optical coherence tomography
- climate change
- positron emission tomography
- label free
- high speed