Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells.

Michael Bordonaro Darina Lazarova Lazarova

Published in: JMIR research protocols (2016)

The findings generated from this study will lead to future, more in-depth projects to further dissect the action of CBP/p300 Wnt-mediated transcriptional programs in colonic neoplasia, with an emphasis on methods to modulate these genetic programs for chemopreventive effect.

Keyphrases

public health
induced apoptosis
gene expression
cell cycle arrest
ulcerative colitis
stem cells
cell proliferation
high grade
transcription factor
current status
genome wide
oxidative stress
cell death
mass spectrometry
high resolution