Dosimetric Validation of a GAN-Based Pseudo-CT Generation for MRI-Only Stereotactic Brain Radiotherapy.
Vincent BourbonneVincent JaouenClément HognonNicolas BoussionFrançois LuciaOlivier PradierJulien BertDimitris VisvikisUlrike SchickPublished in: Cancers (2021)
Our study is the first to compare GAN-generated CT scans from diagnostic brain MRIs with initial CT scans for the planning of brain stereotactic radiotherapy. We found high similarity between the planning CT and the synthetic CT for both the organs at risk and the target volumes. Prospective validation is under investigation at our institution.
Keyphrases
- contrast enhanced
- dual energy
- computed tomography
- image quality
- magnetic resonance imaging
- radiation therapy
- resting state
- positron emission tomography
- white matter
- early stage
- magnetic resonance
- diffusion weighted imaging
- locally advanced
- functional connectivity
- radiation induced
- squamous cell carcinoma
- subarachnoid hemorrhage
- brain injury
- pet ct