Investigating the linkage between mesopic spatial summation and variations in retinal ganglion cell density across the central visual field.
Aoife M L HunterRoger S AndersonTony RedmondDavid F Garway-HeathPádraig J MulhollandPublished in: Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) (2023)
Ricco's area and the number of RGCs underlying RA do not vary significantly across the central visual field in mesopic conditions. However, RA is larger and more similar to the standard perimetric Goldmann III stimulus under mesopic compared with photopic adaptation conditions. Further work is required to determine if compensatory enlargements in RA occur in age-related macular degeneration, to establish the optimal stimulus parameters for AMD-specific microperimetry.
Keyphrases
- age related macular degeneration
- rheumatoid arthritis
- disease activity
- ankylosing spondylitis
- single cell
- interstitial lung disease
- cell therapy
- systemic lupus erythematosus
- gene expression
- stem cells
- mesenchymal stem cells
- human immunodeficiency virus
- hiv infected
- hiv testing
- men who have sex with men
- high density