Cohort profile: SUPER-Finland - the Finnish study for hereditary mechanisms of psychotic disorders.

Markku Lähteenvuo Ari V Ahola-Olli Kimmo SuokasMinna HolmZuzanna MisiewiczTuomas JukuriTeemu MännynsaloAsko WegeliusWillehard HaakiRisto KajanneAija KyttäläAnnamari Tuulio-HenrikssonKaisla LahdensuoKatja HäkkinenJarmo HietalaTiina PaunioJussi Niemi-PynttäriTuula KieseppäJuha VeijolaJouko LönnqvistErkki IsometsäOlli KampmanJari TiihonenSteven HymanBenjamin NealeMark DalyJaana SuvisaariAarno Palotie

Published in: BMJ open (2023)

Compare the effects of common variants, rare variants and copy number variations (CNVs) on severity of psychotic illness. In addition, we aim to track longitudinal course of illness based on nation-wide register data to estimate how phenotypic and genetic differences alter it.

Keyphrases

copy number
mitochondrial dna
genome wide
bipolar disorder
dna methylation
electronic health record
gene expression
big data
data analysis
artificial intelligence
deep learning