Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity.
Silvia CascianelliChiara BarberaAlexandra Ambra UllaElena GrassiBarbara LupoDiego PasiniAndrea BertottiLivio TrusolinoEnzo MedicoClaudio IsellaMarco MasseroliPublished in: Genome medicine (2023)
These results show that CRIS subtypes retain their biological and clinical features even when concomitantly assigned to the same CRC sample. This approach could be potentially extended to other cancer types and classification systems.