Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications.
Ruslan RustRebecca Z WeberMelanie GeneraliDebora KehlChantal BodenmannDaniela UhrDebora WannerKathrin J ZürcherHirohide SaitoSimon P HoerstrupRoger M NitschChristian TackenbergPublished in: Journal of translational medicine (2022)
We describe the generation of transgene- and xeno-free NPCs. This simple differentiation protocol combined with the ability of in vivo cell tracking presents a valuable tool to develop safe and effective cell therapies for various brain injuries.