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Cryopreservation of rare pediatric red blood cells for support following bone marrow transplant.

Kathleen K KellyLouise HelanderKelsey HazeghCrystal StanleyRaymond MossSamantha MackMary L SandersJanice GurleyChris McKinneyLarry J DumontKyle Annen
Published in: Transfusion (2022)
Customized WB collection, glycerolization, freezing, and deglycerolization processes were developed to successfully support a pediatric patient with CGD and MLS after autologous HSCT. Both pediatric units showed increased membrane rigidity post-deglycerolization which may be a consequence of the CGD and MLS genetic background.
Keyphrases
  • bone marrow
  • red blood cell
  • mesenchymal stem cells
  • genome wide
  • hematopoietic stem cell
  • childhood cancer