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EMT-Related Genes Have No Prognostic Relevance in Metastatic Colorectal Cancer as Opposed to Stage II/III: Analysis of the Randomised, Phase III Trial FIRE-3 (AIO KRK 0306; FIRE-3).

Elise PretzschVolker HeinemannSebastian StinzingAndreas BenderShuo ChenJulian Walter HolchFelix Oliver HofmannHaoyu RenFlorian BöschHelmut KüchenhoffJens WernerMartin Konrad Angele
Published in: Cancers (2022)
Overall, the results suggest that the prognostic relevance of EMT-related genes may be stage-dependent and that EMT-related genes have no prognostic relevance in stage IV CRC.
Keyphrases
  • phase iii
  • open label
  • clinical trial
  • epithelial mesenchymal transition
  • metastatic colorectal cancer
  • double blind
  • phase ii
  • placebo controlled
  • study protocol
  • signaling pathway