Impact of the size of the normal database on the performance of the specific binding ratio in dopamine transporter SPECT.
Helen Schmitz-SteinkrügerCatharina LangeIvayla ApostolovaHolger AmthauerWencke LehnertSusanne KlutmannRalph BuchertPublished in: EJNMMI physics (2020)
The results of this study suggest that 25 to 30 is the minimum size of the normal database to reliably achieve good performance of semi-quantitative analysis in dopamine transporter (DAT) SPECT, independent of the algorithm used for image reconstruction and the ROI method used to estimate the putaminal SBR.