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Rh(III)-Catalyzed Cyclopropanation of Unactivated Olefins Initiated by C-H Activation.

Erik J T PhippsTiffany PiouTomislav Rovis
Published in: Synlett : accounts and rapid communications in synthetic organic chemistry (2019)
We have developed a Rh(III)-catalyzed cyclopropanation of unactivated olefins initiated by an alkenyl C-H activation. A variety of 1,1-disubstituted olefins undergo efficient cyclopropanation with a slight excess of alkene stoichiometry. A series of mechanistic interrogations implicate a metal-carbene as an intermediate.
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