Abdominal Obesity-Metabolic Syndrome 3 Misclassified as Type 1 Diabetes Mellitus.
Suhaib RadiLujain BashamakhHayfa MandourahSarah AlsharifPublished in: JCEM case reports (2024)
Age is no longer the most important differentiating feature between type 1 and type 2 diabetes, as obesity and metabolic syndrome are on the rise in the pediatric population. Here we present a case of a 30-year-old male individual initially diagnosed with uncontrolled type 1 diabetes mellitus (T1DM) since the age of 15, and treatment with high insulin doses has been unsuccessful. He was later identified as having abdominal obesity-metabolic syndrome 3 (AOMS3) based on strong family history and the presence of insulin resistance features. AOMS3 is characterized by early-onset coronary artery disease, central obesity, hypertension, and diabetes. Early detection of this condition is crucial to implement timely interventions and preventing the onset of complications.
Keyphrases
- metabolic syndrome
- insulin resistance
- glycemic control
- type diabetes
- early onset
- high fat diet induced
- high fat diet
- coronary artery disease
- adipose tissue
- weight loss
- cardiovascular risk factors
- polycystic ovary syndrome
- uric acid
- skeletal muscle
- blood pressure
- late onset
- cardiovascular disease
- magnetic resonance imaging
- machine learning
- percutaneous coronary intervention
- physical activity
- acute coronary syndrome
- cardiovascular events
- weight gain
- body mass index
- magnetic resonance
- risk factors
- computed tomography
- aortic valve