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Aged IRF3-KO Mice are Protected from Sepsis.

Dinesh G GoswamiWendy E Walker
Published in: Journal of inflammation research (2021)
These results demonstrate that IRF3 plays a detrimental role in sepsis in aged mice and highlight the impact of biological sex.
Keyphrases
  • high fat diet induced
  • acute kidney injury
  • intensive care unit
  • septic shock
  • dendritic cells
  • type diabetes
  • wild type
  • immune response
  • skeletal muscle