Left Ventricular Non-Compaction Cardiomyopathy-Still More Questions than Answers.
Jerzy PaluszkiewiczAndreas BrodehlMarta Kaluzna-OleksyMałgorzata PydaMagdalena JanusHermann KöerperichMisagh PiranPublished in: Journal of clinical medicine (2022)
Left ventricular non-compaction (LVNC) describes the phenotypical phenomena characterized by the presence of excessive trabeculation of the left ventricle which forms a deep recess filled with blood. Considering the lack of a uniform definition of LVNC as well as the "golden standard" it is difficult to estimate the actual incidence of the disease, however, seems to be overdiagnosed, due to unspecific diagnostic criteria. The non-compacted myocardium may appear both as a disease representation or variant of the norm or as an adaptive phenomenon. This article covers different approaches to incidence, pathogenesis, diagnostics, and treatment of LVNC as well as recommendations for patients during follow-up.
Keyphrases
- left ventricular
- heart failure
- end stage renal disease
- mitral valve
- risk factors
- ejection fraction
- aortic stenosis
- chronic kidney disease
- newly diagnosed
- hypertrophic cardiomyopathy
- acute myocardial infarction
- cardiac resynchronization therapy
- prognostic factors
- peritoneal dialysis
- left atrial
- pulmonary hypertension
- pulmonary artery
- coronary artery disease
- coronary artery
- physical activity
- aortic valve
- pulmonary arterial hypertension
- percutaneous coronary intervention
- transcatheter aortic valve replacement
- congenital heart disease
- weight loss