Neutralization of interleukin-38 exacerbates coxsackievirus B3-induced acute myocarditis in mice.

Neutralization of IL-38 exacerbates CVB3-induced AVMC in mice, which may be attributable to the imbalance of Th1/Th17 cells and increased CVB3 replication. Thus, IL-38 can be considered as a potential therapeutic target for AVMC.