Genetic evidence for the most common risk factors for chronic axonal polyneuropathy in the general population.

Noor E TaamsMaria J KnolRens HanewinckelJudith DrenthenHieab H H AdamsPieter A van DoornMohammad Arfan Ikram

Published in: European journal of neurology (2022)

This study provides evidence for polygenic associations of diabetes, BMI, vitamin B12 level, and alcohol intake with chronic axonal polyneuropathy. This supports the hypothesis of causal associations between well-known clinical risk factors and polyneuropathy.

Keyphrases

risk factors
spinal cord injury
type diabetes
cardiovascular disease
weight gain
body mass index
genome wide
optic nerve
glycemic control
copy number
metabolic syndrome
adipose tissue
drug induced
skeletal muscle
weight loss