Blood tissue Plasminogen Activator (tPA) of liver origin contributes to neurovascular coupling involving brain endothelial N-Methyl-D-Aspartate (NMDA) receptors.
Jonathane FuronMervé YetimElsa PouettreSara Martinez de LizarrondoEric MaubertYannick HommetLaurent LebouvierZe ZhengCarine AliDenis VivienPublished in: Fluids and barriers of the CNS (2023)
These data highlight a new mechanism of regulation of NVC involving both endothelial tPA and NMDARs.