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Patterns of TDP-43 Deposition in Brains with LRRK2 G2019S Mutations.

Julian Agin-LiebesRichard A HickmanJean Paul VonsattelPhyllis L FaustXena FlowersIrina Utkina SosunovaJoel NtiriRichard MayeuxMatthew SurfaceKaren MarderStanley FahnSerge PrzedborskiRoy N Alcalay
Published in: Movement disorders : official journal of the Movement Disorder Society (2023)
Extranuclear TDP-43 aggregates are observed with greater frequency in LRRK2 G2019S autopsies compared to PD cases without a LRRK2 G2019S mutation. The association between LRRK2 and TDP-43 should be further explored. © 2023 International Parkinson and Movement Disorder Society.
Keyphrases
  • amyotrophic lateral sclerosis