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Understanding the interplay between the proteasome pathway and autophagy in response to dual PI3K/mTOR inhibition in myeloma cells is essential for their effective clinical application.

L I AronsonE L DavenportFabio MirabellaG J MorganF E Davies
Published in: Leukemia (2013)
Keyphrases
  • induced apoptosis
  • endoplasmic reticulum stress
  • cell cycle arrest
  • cell death
  • signaling pathway
  • oxidative stress
  • cell proliferation
  • multiple myeloma
  • newly diagnosed