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Multiple predictive biomarker testing in melanoma: Another challenge in identifying the optimal approach on cytological samples.

Antonino IaccarinoMariantonia NacchioGennaro AcanforaPasquale PisapiaUmberto MalapelleClaudio BellevicineGiancarlo TronconeElena Vigliar
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)
We highlighted the feasibility of assessing PD-L1 expression levels in residual CB material from metastatic melanomas previously tested for BRAF and NRAS mutations. Moreover, we pointed out that FNC needle rinses may be an alternative source of nucleic acids for molecular testing, preserving CB material for immunocytochemistry evaluation.
Keyphrases
  • small cell lung cancer
  • squamous cell carcinoma
  • wild type
  • ultrasound guided
  • fine needle aspiration
  • metastatic colorectal cancer