The CYP17 MspA1 Polymorphism and the Gender Dysphoria.
Rosa FernándezJoselyn Cortés-CortésIsabel EstevaEsther Gómez-GilMari Cruz AlmarazEstefanía LemaTeresa RumboJuan-Jesús Haro-MoraEster RodaAntonio GuillamónEduardo PásaroPublished in: The journal of sexual medicine (2015)
Our data confirm a sex-dependent allele distribution of the CYP17 MspA1 polymorphism in the transsexual population, FtM > MtF, suggestive of a hypothetical A2 involvement in transsexualism since the allele frequencies in the general population seem to be clearly related to geographic origin and ethnic background, but not sex.