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Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses.

Karolina SeborovaRadka VaclavikovaPavel SoucekKaterina ElsnerovaAlena BartakovaPetr CernajJiri BoudaLukas RobMartin HrudaPavel Dvořák
Published in: Cancer medicine (2019)
This study stressed the connection between two well-documented ABC genes and clinicopathological features-ABCB1 and ABCG2. Moreover, we showed a comparable connection also for several other ABC genes-ABCB11, ABCC4, ABCC10, ABCD3, ABCE1, ABCF1, ABCF2, and ABCF3. Our results add new clinically relevant information to this oncology field and can stimulate further exploration.
Keyphrases
  • genome wide
  • genome wide identification
  • genome wide analysis
  • bioinformatics analysis
  • palliative care
  • dna methylation
  • gene expression
  • healthcare
  • social media