Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses.
Karolina SeborovaRadka VaclavikovaPavel SoucekKaterina ElsnerovaAlena BartakovaPetr CernajJiri BoudaLukas RobMartin HrudaPavel DvořákPublished in: Cancer medicine (2019)
This study stressed the connection between two well-documented ABC genes and clinicopathological features-ABCB1 and ABCG2. Moreover, we showed a comparable connection also for several other ABC genes-ABCB11, ABCC4, ABCC10, ABCD3, ABCE1, ABCF1, ABCF2, and ABCF3. Our results add new clinically relevant information to this oncology field and can stimulate further exploration.