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RUNX3 alleviates mitochondrial dysfunction and tubular damage by inhibiting TLR4/NF-κB signalling pathway in diabetic kidney disease.

Ling XiaoGang Ye
Published in: Nephrology (Carlton, Vic.) (2024)
SMURF2 interference inhibits RUNX3 ubiquitination and TLR4/NF-κB signalling pathway, thereby alleviating renal tubule injury.
Keyphrases
  • signaling pathway
  • nuclear factor
  • inflammatory response
  • lps induced
  • toll like receptor
  • oxidative stress
  • transcription factor
  • pi k akt
  • immune response
  • type diabetes
  • mouse model
  • cell proliferation