Associations of combined genetic and epigenetic scores with muscle size and muscle strength: a pilot study in older women.

Lingxiao He Praval Khanal Christopher Ian Morse Alun Gwyn Williams Martine A I Thomis

Published in: Journal of cachexia, sarcopenia and muscle (2020)

Our results improve the understanding of inter-individual variance in muscular characteristics of older women and suggest a possible application of a sarcopenia-driven methylation score to muscle strength estimation in older women while the combination with a genetic score still needs to be further studied.

Keyphrases

genome wide
dna methylation
skeletal muscle
copy number
gene expression