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miRNA-seq identification and clinical validation of CD138+ and circulating miR-25 in treatment response of multiple myeloma.

Maria-Alexandra PapadimitriouKonstantinos SoureasAristea-Maria PapanotaPanagiotis TsiakanikasPanagiotis G AdamopoulosIoannis Ntanasis-StathopoulosPanagiotis MalandrakisMaria GavriatopoulouDiamantis C SiderisEfstathios KastritisMargaritis AvgerisMeletios-Athanasios DimopoulosEvangelos TerposAndreas Scorilas
Published in: Journal of translational medicine (2023)
Our study identified miR-25 overexpression as a powerful independent predictor of poor treatment outcome and post-treatment progression, aiding towards modern non-invasive disease prognosis and personalized treatment decisions.
Keyphrases
  • cell proliferation
  • long non coding rna
  • multiple myeloma
  • long noncoding rna
  • genome wide
  • combination therapy
  • single cell
  • replacement therapy