B-type natriuretic peptide in low-risk pregnancy and pregnancy with congenital heart disease.

Francois Dos SantosNatalie DennehyPhilip J SteerMark R Johnson

Published in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2023)

This study assessed BNP longitudinally in the first, second and third trimesters in singleton low-risk pregnancy, and showed that BNP concentration decreased with advancing gestational age, with no participants with levels greater than 40.0 pg/mL in the third trimester. BNP concentrations were similar in women with and without congenital heart disease. We found no correlation between circulating levels of BNP and maternal hemodynamics at rest or with exercise measured by ICG to support its use as a marker of cardiac function.

Keyphrases

preterm birth
gestational age
birth weight
congenital heart disease
pregnancy outcomes
pregnant women
high intensity
physical activity
fluorescence imaging